mississippi river cruise new orleans to chicago

7 best Mississippi River cruises

Mississippi River cruises have surged in popularity in recent decades. They are especially appealing to mature travelers looking to enjoy guided tours of top cities and small towns in several Southern and Midwestern states.

Add in regionally inspired cuisine enjoyed aboard a luxurious river ship, plus the camaraderie of other culturally curious travelers, and cruising the most celebrated river in the United States promises satisfaction on multiple levels.

Two major cruise lines sail the Mississippi, which stretches 2,340 miles from New Orleans to Minneapolis-St. Paul: American Cruise Lines and Viking . Each line offers several similar itineraries ranging from eight to 23 days, but the ships themselves differ. Some are retro-inspired paddlewheelers, others sleek modern riverboats. The onboard dining and entertainment, as well as the excursions in port, also vary across the lines.

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We've rounded up the best Mississippi River cruises for seniors, history buffs and Americana lovers, so you can find your perfect U.S. river cruise itinerary based on your interests and travel preferences.

Best cruise for Civil War history: Lower Mississippi (round trip from New Orleans)

The Deep South attracts history buffs with its Civil War battlefields and cemeteries and 18th- and 19th-century mansions guarded by regiments of live oaks. Both cruise lines offer a Lower Mississippi river cruise, sailing round-trip from New Orleans, but only one features multiple excursions geared to those with a keen interest in the 19th-century conflict.

On American Cruise Lines' eight-day New Orleans to New Orleans itinerary , cruisers can visit Vicksburg, Mississippi, where the National Military Park commemorates the campaign, siege and defense of Vicksburg in 1863. In Louisiana's capital, Baton Rouge, a guided excursion explores critical locations in the Civil War's Battle of Baton Rouge and Port Hudson.

Other ports bring to life the pre-war South. In Oak Alley, Louisiana, guests can tour a Greek Revival mansion on a sugar plantation built and maintained by slaves. While no Civil War fighting took place in Natchez, Mississippi, the city is home to hundreds of lavish mansions from the era and the Historic Natchez Cemetery, which dates to 1822.

This itinerary is offered in 2024 and 2025 on four American Cruise Lines ships, ranging from the 150-passenger classic paddlewheeler American Heritage to the 180-passenger modern riverboat American Serenade. American Cruise Lines is known for its regionally inspired cuisine, served with complimentary wine and beer at lunch and dinner, plus complimentary cocktails, hors d'oeuvres and hosted entertainment in the main lounges.

Some excursions and a pre-cruise hotel stay in the Big Easy are included in the cruise fare. You can book additional day tours for an extra cost.

Related: Best river cruise lines around the world

If you're especially passionate about Civil War history, look for American Cruise Lines' special Civil War-themed cruises on limited dates, which allow a deeper dive into the period. These include a nine-day Lower Mississippi itinerary from Memphis to New Orleans (or vice versa).

In addition to visiting monuments and museums, you'll enjoy onboard lectures and presentations and interaction with other Civil War buffs. These sailings are aboard 150-passenger American Heritage and 180-guest American Melody, American Serenade, American Splendor and American Symphony.

Best cruise for music: Lower Mississippi (New Orleans to Memphis)

If you love the musical genres of the South, a Mississippi River cruise from New Orleans to Memphis (or vice versa) should be your choice.

From Crescent City, the birthplace of American jazz, to Memphis, known as the Home of the Blues and the Birthplace of Rock 'n Roll, this itinerary celebrates the region's homegrown rhythms. Both cruise lines offer itineraries between New Orleans and Memphis, but Viking features more excursions and onboard experiences tailored to music lovers.

Viking's 12-day Heart of the Delta itinerary includes a two-night pre-cruise hotel stay in New Orleans. This allows ample time to enjoy the city's street musicians and jazz clubs.

In Baton Rouge, you can visit the Capitol Park Museum, which showcases exhibits dedicated to Louisiana's musical heritage and Mardi Gras traditions. While in Natchez, Mississippi, classical music (played on a 1903 Steinway piano) and Southern cuisine are the stars of the excursion to Lansdowne and Joseph Stone House.

The port call in Greenville, Mississippi, is steeped in the blues with a chance to visit a museum dedicated to hometown legend B.B. King. The grand finale of the cruise is two nights in Memphis, where you can enjoy all things blues, barbecue and Elvis Presley.

Viking is a newcomer to the Mississippi River, and all sailings are aboard the 386-guest Viking Mississippi. The riverboat debuted in 2022 and features a modern Scandinavian design. Itinerary departures are available in 2024 and 2025.

Passengers can enjoy a sun terrace with an aft infinity pool and an Explorer's Lounge with panoramic forward views of the Mississippi. The Restaurant serves both Southern regional cuisine and global favorites, and the ship welcomes local musicians onboard for evening entertainment.

Related: Meet the only line that cruises from Washington, DC. Here's where it'll take you

Best cruise for art and architecture: Upper Mississippi

An Upper Mississippi cruise between St. Louis, Missouri, and St. Paul, Minnesota, provides access to some of the top architectural landmarks and artistic treasures of the American Heartland — from Eero Saarinen's soaring Gateway Arch to Frank Lloyd Wright's inimitable Taliesin.

Both cruise lines offer Upper Mississippi sailings from July through September. Viking and American Cruise Lines' itineraries and excursions are our picks for fans of American art and architecture.

Viking River Cruises' American Heartland itinerary sails from St. Louis to St. Paul (or vice versa) and runs 12 days with pre- and post-cruise stays in 2024 and 2025. You'll explore architectural gems aboard Viking Mississippi, itself an example of sleek, Scandinavian-inspired nautical architecture.

Highlights include St. Louis, where you'll admire Saarinen's circa-1965 Gateway Arch, the Cathedral Basilica of St. Louis featuring a 41-million-piece mosaic and the Renaissance Revival-style City Hall. From Dubuque, Iowa, you can head to Spring Green, Wisconsin, to visit Taliesin, Frank Lloyd Wright's private home, studio and school from 1911 to 1959.

After a day in Redwing, Minnesota, known for its pottery studios, you'll end your journey in the Twin Cities, home to the Walker Art Center and Minneapolis Institute of Art in Minneapolis and well-preserved Victorian buildings in St. Paul.

Related: River cruise packing list: What to pack when traveling by riverboat

American Cruise Line's nine-day Upper Mississippi river cruise covers much of the same ground, with a few differences. Sailings are available on the 150-passenger paddlewheeler American Heritage as well as on three sleek new 180-guest riverboats, American Melody, American Serenade and American Symphony. They're offered between June and late September/early October in 2024, 2025 and 2026.

Beyond the landmarks of St. Louis, highlights include Hannibal, Missouri, where you can visit the Mark Twain Boyhood Home and Museum, and Dubuque, Iowa, known for its colorful Victorian mansions. (An excursion to the Field of Dreams featured in the 1989 Kevin Costner movie is also available.)

Winona, Minnesota, boasts some of the state's most architecturally significant buildings, many featuring the beautiful stained glass for which the city is known. Then it's off to Red Wing, Minnesota, where you can explore the Pottery Museum before completing your journey in the Twin Cities.

Best extended cruise: Complete Mississippi

Want it all? You can visit 18 ports in six states on a 23-day Mississippi River journey from New Orleans to St. Paul. These itineraries are offered by both American Cruise Lines and Viking, and are perfect for seniors with plenty of time to explore.

American Cruise Lines offers the 23-day Complete Mississippi Cruise in 2024, 2025 and 2026, with sailings available on three 180-passenger modern river ships: American Melody, American Serenade and American Symphony.

After a pre-cruise hotel stay in New Orleans, passengers journey through all aspects of American history. You'll visit ports known for ornate mansions (Oak Alley and St. Francisville, Louisiana, and Natchez, Mississippi), Civil War battles (Baton Rouge, Louisiana and Vicksburg, Mississippi), music (Memphis and Greenville, Tennessee) and architecture (St. Louis and Dubuque, Iowa). You'll also call on a historic Missouri trading post in Cape Girardeau (a French river port).

Viking River Cruises' 22-day Grand Mississippi Voyage , available in 2024 aboard the 386-passenger Viking Mississippi, also embarks in New Orleans and visits 16 ports in nine states as it cruises north to St. Paul, Minnesota.

During this sailing, you'll overnight in Memphis, so there's time to fully savor barbecue, the blues and Elvis Presley's Graceland. A port call in Paducah, Kentucky, lets you explore the National Quilt Museum and colorful street murals.

You can enjoy excursions in Missouri's most famous big city (St. Louis) and small town (Hannibal) and then visit three ports in Iowa known for their historic architecture and agriculture (including a tour of the John Deere Pavilion). Learn about the Norwegian heritage of La Crosse, Wisconsin, and get to know the eagles and pottery of Red Wing, Minnesota, before disembarking in St. Paul.

Bottom line

History buffs and Americana lovers will find plenty to enjoy on a Mississippi River cruise. Your ship will stop in major cities and lesser-known towns, offering excursions to historic sites and evenings spent enjoying locally inspired cuisine and regional music.

The two cruise lines sailing America's most legendary river offer itineraries for every interest on ships designed with mature travelers in mind. Whether you want to visit Civil War sites, see top architectural landmarks or enjoy our country's best-loved musical genres, these two lines will offer a Mississippi River itinerary that will help you do it — in comfort and style as you make new friends on board.

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Upper Mississippi River Cruises

Thinking about hopping aboard a USA River Cruise to explore the Upper Mississippi? Then you’ve got a lot to look forward to — and a little planning to do.

But don’t worry. It’s the fun kind of planning. The kind when you choose from a tremendous variety of Mississippi River cruises and pick the one that best suits your tastes and interests.

USA River Cruises has so many cruises along the Upper Mississippi River that we sometimes have a hard time confining them to one page of our website!

What’s on your itinerary? Let’s look at just a few — and we’d like to stress again just how many options there are!

The first trip we’ll mention really puts the Upper in Upper Mississippi — an eight days, seven nights cruise from St. Louis, Missouri, to Minneapolis, Minnesota.

The Upper Mississippi River is stunning, inspirational, and for many people the more scenic half of the waterway. You’ll explore the world where the former Samuel Clemens (pen name: Mark Twain) grew up. Twain, raised in Hannibal, Missouri, actually worked for a time as a riverboat pilot on the mighty Mississippi. You’ll also get to see much of the American heartland, including Dubuque, Iowa, La Crosse, Wisconsin, and Red Wing, Minnesota.

And if you’re interested in the trip downriver instead of up, well, USA River Cruise can reverse this itinerary for you, too!

Next, consider expanding your trip to encompass the whole shebang: We call it the Complete Mississippi River Cruise, and the name is apt.

You’ll spend a full three weeks aboard ship as you cruise the length of the second-longest river in North America — from New Orleans, Louisiana, to St. Paul, Minnesota. You’ll visit big towns (Memphis, St. Louis, and more) and small towns (Vicksburg, Mississippi, and Chester, Illinois, where you can get a picture of a tall bronze statue of Popeye, whose creator, E. C. Segar, is from Chester).

You’ll have to act fast for this one, though. USA River Cruises only offers this trip once per year!

Call today!

Upper Mississippi Explorer

Memphis, TN to St. Paul, MN

• June 29, 2024, August 3, 2024, October 5, 2024
• From $8,999
• Viking Mississippi
• New Itinerary!! Save up to $1000 off per Stateroom plus Discounted Air!!

Grand Heartland Cruise-American Serenade

St. Paul to New Orleans

• September 17, 2024, August 15, 2025
• From $11,090
• American Serenade

Grand Heartland Cruise-American Melody

• August 2, 2024, October 17, 2025
• From $11,755
• American Melody

Grand Heartland Cruise-American Symphony

• October 4, 2024
• From $11,255
• American Symphony

Upper Mississippi River Cruise: St. Louis – St.Paul

St. Louis to St. Paul

• September 20, 2024, September 27, 2024
• From $5,545

Complete Mississippi River Cruise-American Symphony

New Orleans to St. Paul

• August 30, 2024
• From $16,640

Complete Mississippi River-American Serenade

• June 18, 2024
• July 9, 2024, July 16, 2024, July 23, 2024 -- 7 more dates available.

Viking-America’s Great River

St Paul to New Orleans

• July 13, 2024, September 14, 2024, October 19, 2024 -- 3 more dates available.
• From $12,999

Viking-America’s Heartland

St Louis to St Paul

• August 15, 2024, August 22, 2024, August 29, 2024 -- 8 more dates available.
• From $6,999

Upper Mississippi River Cruise-American Melody

• June 21, 2024, July 26, 2024

Complete Mississippi River-American Melody

• May 31, 2024
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What to Know About Mississippi River Cruises — From the Cruise Lines to Top Itineraries

See small towns and bustling cities by boat on a Mississippi River cruise.

Elizabeth Rhodes is a special projects editor at Travel + Leisure , covering everything from luxury hotels to theme parks to must-pack travel products. Originally from South Carolina, Elizabeth moved to New York City from London, where she started her career as a travel blogger and writer.

River cruises are a great way to see the world — you can visit several waterfront destinations and watch the scenery pass by from cozy accommodations and top-deck lounges on intimate luxury ships. And while rivers like the Danube and the Rhine are top choices for many travelers, you don't have to go abroad for a memorable river cruise. You can access some of the nation's iconic attractions and favorite cities right from the Mississippi River.

There are three main cruise lines traveling the Mississippi, with journeys ranging from less than a week to more than 20 days. Spring and fall are the best times of year to take a cruise along the river, as you'll avoid the summer heat and winter chill and enjoy more pleasant weather while you take in the surroundings.

Here's what you need to know about Mississippi River boat cruises, from choice itineraries to popular stops.

Mississippi River Cruise Lines

There are three main cruise lines that offer itineraries along the Mississippi River: Viking River Cruises , American Queen Voyages , and American Cruise Lines . Viking is known for its luxury river, ocean, and expedition cruises to incredible destinations around the world, and trips aboard its 193-stateroom Viking Mississippi adhere to the same standard of service.

American Queen Voyages offers several itineraries along the Mississippi — one along the Upper Mississippi, another on the Lower Mississippi, and one that also sails a portion of the Ohio River — on its signature paddle-wheel steamboats. The company's flagship, the American Queen, is said to be the world's biggest steamboat.

The itineraries on American Cruise Lines feature either modern riverboats or old-school paddle wheelers, so you can choose your ideal sailing experience.

All three cruise lines offer similar itineraries along the river, so we recommend looking into the ships, the amenities, and what's included in the rate (like pre-departure hotel stays and excursions) to help make your decision.

Popular Ports on the Mississippi

You can cruise all the way from New Orleans to Minneapolis, or you can sail shorter segments of the river. Typically, cruises along the Lower Mississippi sail between New Orleans and Memphis, while cruises on the Upper Mississippi sail between St. Louis and the Twin Cities.

Passengers on the Upper Mississippi may get the chance to hop off and explore Mark Twain's childhood home in Hannibal, Missouri, stroll the streets of Iowa's oldest city (Dubuque), or marvel at sacred bluffs in Red Wing, Minnesota. Along the Middle Mississippi, there's Paducah, Kentucky, a UNESCO-designated Creative City , and Chester, Illinois, the birthplace of Popeye the Sailor Man.

On the Lower Mississippi, you'll find Cajun culture in Baton Rouge, Louisiana, Civil War history in Vicksburg, Mississippi, and music and BBQ in Memphis .

Mississippi River Cruise Itineraries

There are many itineraries to choose from between the three major Mississippi River Cruise lines, but here are our top picks.

Viking River Cruises: America's Great River

Cruise from New Orleans all the way up to St. Paul on Viking's 15- or 17-day America's Great River itinerary aboard the 193-stateroom Viking Mississippi , a vessel designed just for this river. The journey starts in New Orleans and stops in Baton Rouge; Natchez and Vicksburg, Mississippi; Memphis; and St. Louis, where passengers can explore attractions like Gateway Arch National Park and the flagship Anheuser-Busch brewery. From there, it continues on to Hannibal, Missouri; Burlington, Davenport, and Dubuque, Iowa; La Crosse, Wisconsin; and Red Wing, Minnesota, where travelers can learn about America's most recognizable symbol at the National Eagle Center. In between action-packed stops, there's plenty of time to take in the scenery from your veranda or the boat's several public viewing areas.

American Queen Voyages: New Orleans to Memphis

Sail along the Lower Mississippi from New Orleans to Memphis on this nine-day cruise, which starts with a complimentary stay in New Orleans and a second day to enjoy the Big Easy. Then, it's on to Nottoway Resort and St. Francisville in Louisiana and Natchez, Vicksburg, and Greenville in Mississippi before a day of cruising through the Delta and disembarking in Memphis. There are a few different paddle-wheel riverboats that cruise this route for American Queen Voyages — find the specific ship for your journey when you select a date.

American Cruise Lines: Upper Mississippi River Cruise

This eight-day cruise starts in St. Louis and sails along the Upper Mississippi to St. Paul. Stops along the way include Hannibal, Missouri; Fort Madison, Davenport, and Dubuque, Iowa; and Winona and Red Wing, Minnesota. Several riverboats cruise this route, including American Melody and American Symphony , inaugurated in 2021 and 2022, respectively. These sister vessels offer large rooms and suites with contemporary furnishings and an upscale feel.

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Mississippi River Dinner Jazz Cruise

Step on board and cruise with us into the night where the sleepless activity of America's busiest port buzzes. The sounds of a lively jazz band fill the air as you enjoy a lavish Creole buffet in elegantly appointed dining rooms. See details

Historical River Cruise

View the French Quarter, the Port of New Orleans, and Jean Lafitte National Historical Park and Preserve and be entertained by a historian narrator with a detailed description of New Orleans landmarks, history, vessel information, and river lore. See details

Weekend Jazz Brunch

Enjoy delicious brunch delicacies as you cruise down the Mighty Mississippi River while listening to the lively sounds of a traditional New Orleans Jazz band See details

Valentine's Day River Cruise

Mother's Day Bubbly Brunch

Fourth of July Celebration Cruise

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U. S. River Cruises

A river cruise along the Mississippi offers an amazing way for you to see the U.S. and connect with history.

As you cruise from north to south or vice versa on the Mississippi River you’ll be making stops in towns that have played a significant role in the American story. Take for instance Springfield, Ill. Where Abraham Lincoln spent much time. You can also travel to the top of the magnificent St. Louis Arch for an incredible view of St. Louis and the Mississippi. 

Things to Do on the Mississippi River Cruise

The cities and towns that line the Mississippi River are jam-packed with stories, people and food that will leave an indelible impression on you. You have everything from New Orleans in the South, with its French and Spanish influences, to Chicago in the North, where the first skyscrapers were built. In between you’ll discover a rich history of music with stops in Nashville and Memphis, and U.S. history at the homes of famous Americans like Abraham Lincoln and Mark Twain. Featured below are some of the best ways to spend your time when cruising along the Mississippi River:

• Find a friend and practice posing like the farmer and his daughter in the classic painting “American Gothic.” You can study the portrait at the acclaimed Art Institute of Chicago, one of America’s best art museums.  
• Don’t be cruel and deprive yourself of a visit to Graceland, the home of the king of rock ‘n’ roll, when you are in Memphis. Elvis’ home may seem modest to the modern eye, but there are a lot of lavish and loud decorations to see.  

• Visit the battlefield in Vicksburg. This town along the Mississippi River was the sight of one of Ulysses S. Grant’s most celebrated achievements. Here he was able to defeat Confederate forces and severely weaken their efforts.  
• Visit the former home of Huey Long, the famous governor of Louisiana, at the Old Governor’s Mansion in Baton Rouge, Louisiana. Many believe that Long was the inspiration for the acclaimed novel and movie, All the King’s Men.  

• Put a little spice into your life when you try some of New Orleans’ classic dishes like gumbo and jambalaya. Afterwards, if you still have room, try beignets or bananas foster for dessert.  
• Enjoy the company of country music royalty when John Carter Cash, the son of Johnny Cash and June Carter Cash, shares his music and stories at the Country Music Hall of Fame in Nashville.  

Map of U.S. River Cruising Region:

Top 10 u. s. river cruises.

• Viking Mississippi 11 Night Heart of the Delta Departing From New Orleans, Louisiana (May 2024 - Jun 2024)
• Viking Mississippi 11 Night Heart of the Delta Departing From Memphis, Tennessee (May 2024 - Jun 2024)
• Viking Mississippi 21 Night Grand Mississippi Voyage Departing From New Orleans, Louisiana (Jun 2024 - Jul 2024)
• Viking Mississippi 7 Night Mississippi Delta Explorer Departing From New Orleans, Louisiana (Jun 2024 - Dec 2025)
• Viking Mississippi 14 Night Upper Mississippi Explorer Departing From Memphis, Tennessee (Jun 2024 - Oct 2024)
• Viking Mississippi 14 Night America's Great River Departing From Saint Paul, United States (Jul 2024 - Oct 2025)
• Viking Mississippi 11 Night America's Heartland Departing From Red Wing, Minnesota (Aug 2024 - Aug 2025)
• Viking Mississippi 11 Night America's Heartland Departing From St. Louis, Missouri (Aug 2024 - Oct 2025)
• Viking Mississippi 7 Night New Orleans & Southern Charms Departing From New Orleans, Louisiana (Nov 2024 - Dec 2025)
• Viking Mississippi 7 Night Mississippi Delta Explorer Departing From Memphis, Tennessee (Jan 2025 - Dec 2025)

U. S. River: Cruise Lines

Enjoy a river cruise along the mighty Mississippi where you can spend time letting the good times roll in New Orleans or yukking it up at a Second City Improv show in Chicago. Experience the lure of this waterway made famous by Mark Twain and the great explorers Lewis and Clark. 

Viking Rivers focuses their sailings on the culture of each cruises destination. Onboard each sailing you have lectures, demonstrations and tastings as part of a Culture Curriculum.

U. S. River: Departure Ports

Mark Twain so vividly described life along the shores of the Mississippi River back in the 1800s, now you can learn about the river in it’s heyday along with the modern cities that line its coast on a river cruise. There are two separate sailings along the mighty Mississippi, one leaving from Chicago and another from Nashville. Both offer amazing stops along the way to see sites like the Grand Ole Opry or Willis Tower (formerly known as The Sears Tower). 

Memphis, Tennessee

Musical Memphis is the perfect port along the Mississippi. Indulge in some classic BBQ before enjoying a lively night on the town.

New Orleans, Louisiana

The Big Easy is one of the world’s most fascinating cities and a melting pot of culture, food and music.

Red Wing, Minnesota

Saint Paul, United States

Explore the quaint city of Saint Paul, where cultures collide for a unique experience along the Mississippi River.

St. Louis, Missouri

Discover culture, beautiful scenery and plenty of beer when you cruise by St. Louis along the Mississippi River.

Photo Gallery for U. S. River Cruises

Take a trip through America’s heartland in our U.S. River photo gallery. While sailing along the Mississippi River, you’ll see classic paddle steamers, soulful Memphis, colorful New Orleans and more – the best of which can only be experienced in person.

French Quarter in New Orleans, Louisiana

Mississippi River in downtown Memphis, Tennessee

Paddle steamer in New Orleans

Oak Alley Plantation in Louisiana

Skyline of Nashville, Tennessee

St. Louis Arch from the Mississippi River

The corner of St. Peter and Bourbon Street

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Zalong the mississippi new orleans to memphis.

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Our Distinctive A+R Style

• Chauffeured privately from the airport to the new 5-Star Higgins Hotel, take time to explore the Quarter, delight in the city’s unique cuisine or visit the award-winning National WWII Museum, New Orleans Number 1 attraction, just next door to the hotel before our guided tour of the city the next morning. Extra nights at the Higgins are available if you wish.
• Embark on a guided boat expedition into the Manchac Bayou where lush vegetation and moss-draped cypress provide prime habitat for a rich variety of wildlife.
• Enjoy a guided visit to iconic Nottoway Plantation, the grandest Antebellum mansion along the Mississippi, and explore the historic towns of St. Francisville and Natchez so expressive of life before, during and after the Civil War era.
• Learn about the siege that captured the Mississippi for the Union at the Vicksburg National Military Park and see the 27 monuments representing the states that lost soldiers in the dramatic conflict.
• Explore the rise of R&B and Rock in the deep musical traditions of the South at venues associated with Ray Charles, B.B. King and, of course, Elvis.
• With private chauffeured airport transfers, a pre-night in New Orleans at our luxury hotel and 7 nights in your choice of outside stateroom; Open Bar; 21 meals; a complete program of 6 pre-arranged premium shore excursions and all shipboard gratuities.

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Welcome to New Orleans

The Higgins Hotel - New Orleans, LA

Your driver will await you at the airport to chauffeur you to the Higgins Hotel , named for Andrew Higgins whose company invented and then produced more than 20,000 shallow-draft ‘swamp boats’ that were critical to the success of the Normandy Landings on D-Day. Attached to the National Word War II Museum, this modern hotel in a restored building carries forward the Art Deco atmosphere of the 1940’s. There’s time to explore the French Quarter, enjoy the unique cuisine of the city or tour the museum. Should you wish more time on your own in New Orleans, we’re pleased to book extra nights at the Higgins for you.

See The Big Easy + Embark the American Countess

American Countess

Following breakfast, we’ll check-out and gather your luggage before departing on a guided tour of New Orleans to explore some of its neighborhoods, the storied French Quarter, St. Louis Cemetery, Jackson Square and City Park. After sightseeing we’ll head to the pier where the elegant American Countess awaits. Settle in to your spacious outside stateroom as we begin our voyage up the Mississippi. With flexible open seating in the dining room throughout the cruise, enjoy the ship’s fine dining anytime between 5 and 8pm enhanced with complimentary house wine and spirits. Of course, the open bar is always at your disposal. Meals B+D

Deep into a Bayou + Nottoway Plantation

After an extensive breakfast, we’ll wind our way along historic River Road to La Place, deep in the heart of Louisiana plantation country, while our expert guide offers colorful insight and historic anecdotes about the region when cotton and sugar were king. Arriving at the edge of the Manchac Bayou, we’ll meet our resident Cajun Captain who’ll guide us in his boat deep into these wetlands – where lush vegetation and moss-draped cypress provide prime habitat for a wide variety of wildlife. American alligators, nutria, ibis, herons and egrets are some of the species we might encounter. Following lunch back on-board, we’ll experience a bit of antebellum life. Surrounded by manicured gardens, Nottoway is a historic 3-story residence with grand, columned verandahs and a lavishly decorated interior including the White Ballroom, entirely white with gold gilding. The White Castle of Louisiana is the perfect example of plantation life of that pre-Civil War era. Returning to the ship in the late afternoon, there will be time to relax before dinner is served. Meals B+L+D

The Charm of St. Francisville

On a bluff overlooking the Mississippi, this lovely town has a colorful early history as the oldest in what are known as Louisiana’s Florida Parishes. In 1810, an adventurer fought off the Spanish to control a group of parishes on the East Bank of the river and designated them the Republic of West Florida. Although the Republic didn’t last long, the identity of the Florida Parishes has persisted to this day. Settled initially as Bayou Sara, floods and fires destroyed the settlement and the hearty residents simply hauled their surviving homes up the bluff to establish themselves anew as the town of St. Francisville. With hop-on, hop-off touring, we’ll explore this historic town with 140 buildings listed in the National Register of Historic Places. Admire the homes along Royal Street and stroll the Old Market Hall, established in 1819. The West Feliciana Historical Society Museum and Grace Episcopal Church are other notable highlights. Meals B+L+D

Natchez, Mississippi

After breakfast on-board, our guests will enjoy a guided visit to The Towers, one of the most elegant private homes in this historically rich town, the oldest along the entire Mississippi. Restored recently by Ginger and James Hyland, they will personally accompany our visit as they present the history, architecture and extensive collections of antiques and fabrics that fill the residence. In the afternoon, following lunch on The Countess, we’ll enjoy independent hop-on, hop-off sightseeing with extensive opportunities to explore antebellum life. Among the stops and places you can explore at your own pace are the Rosalie Mansion, built in 1823, and the remarkable William Johnson House Museum. Mr. Johnson was born a slave who gained his freedom at the age of eleven and built this 3-story brick home during his career as the town’s barber. Both Magnolia Hall and Stanton Hall are other Greek Revival architectural gems to include in your visit. A great place to cap the afternoon is the Museum of African-American History and Culture covering the 300 years of the struggle for equality in the environs of Natchez. Meals B+L+D

Vicksburg, Mississippi

Abraham Lincoln wrote to his commanders early in 1863 “… see what a lot of land these fellows hold, of which Vicksburg is the key. The war can never be brought to a close until that key is in your pocket.” Thus began one of the most consequential campaigns of the Civil War for control of the entire length of the Mississippi. Waged over the course of more than three months in the spring and summer of that year, the terrible Siege of Vicksburg gained the Union success albeit with tremendous losses on both sides. The rich character of the city remains, however, as our hop-on, hop-off independent touring will reveal this morning. The stained-glass windows of the Church of the Holy Trinity, built after the war in 1869, are magnificent. Built in 1830, the nearby Anchuca Mansion was the war hospital during the Siege and is now on the National Register of Historic Places. The antebellum 1858 Old Court House, the Lower Mississippi Museum and Old Depot Museum are interesting inclusions this morning. Surprisingly, the first bottles of Coca-Cola in the world were filled in 1894 at the Biedenharn Coca-Cola Museum, a fun addition to your ramblings in Vicksburg. Following lunch on-board, our guests will depart for a guided excursion to the picturesque Vicksburg National Military Park where we’ll learn the riveting stories of what soldiers endured over the three months of battle to capture the city. The National Military Park houses 27 major monuments erected since 1903 to commemorate all the states that lost soldiers during the Siege, including one that honors the Union’s Mississippi Black Infantry. We’ll visit the Illinois State Monument which ranks among the many here as America’s most impressive military memorials. Before returning to ship, we’ll also visit the USS Cairo, an iron clad river boat that was commissioned in 1862 and raised from the river bottom in 1964. Meals B+L+D

Greenville, Mississippi + BB King

Today, we’ll arrive in Greenville in the late morning. Following lunch, we’ll depart The Countess for our included guided excursion to the B.B. King Museum and Delta Interpretive Center in neighboring Indianola, Mississippi. Dedicated to its native son, our guided tour of this wonderful museum documents B.B. King’s life and presents his key role in introducing the Blues to the world. We’ll finish this memorable afternoon at the Club Ebony, a musical venue that hosted greats like Albert King, Ray Charles and, of course, B.B. King. Meals B+L+D

Cruising North on the Mississippi

Take this day to relax and enjoy the passing scenery as it shifts from bucolic countryside to small, lively river towns. Enriching on-board talks, an Open Bar, elegant dining with wine, and a chance to engage with your fellow passengers highlight this pleasant day on the river and aboard a beautiful ship. Meals B+L+D

Memphis + Elvis

Following breakfast, we’ll gather our luggage and disembark by coach for a guided trip through the city. We’ll walk along famous Beale Street following the footsteps of iconic musicians before a fully-guided tour of Graceland. For those who wish to spend more time in Memphis, we can provide extra nights at The Peabody or we will transfer you to Memphis International Airport for your onward journey. Meals B

American Countess Health Protocols  

• All guests and crew are fully-vaccinated
• Complimentary pre-cruise PCR testing of all guests and crew
• Capacity controls in-place for social distancing on-board and excursions
• New fresh air ventilation and UV-C light for disinfecting microorganisms
• Full sanitation of all services on-board, in staterooms and on motorcoaches
• Staff delivery of all food services, suspended buffets
• Fully-licensed nurse on-board; medical facilities easily accessible for entire voyage

Memphis to New Orleans Southbound Itinerary

Please note, we carry more than 16 guests on this program. Port charges $199 per person are not included

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Every A+R Journey is carefully crafted with more than 7 decades of expertise helping our guests to experience the world in a more authentic and caring way. Choose from more than 105 Original Journeys With Never More than 16 Guests or book your tour as a Completely Private Experience – whether it’s just the two of you, a small group of friends, or your entire family.

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Travel | Orlando native canoes the Mississippi…

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Travel | orlando native canoes the mississippi encountering amazing scenery, angels, villains, solitude.

Maybe that’s why this Orlando native was so fascinated that you can travel by canoe along America’s most famous river from near Canada to the Gulf of Mexico.

Last fall, I finished a solo 92 days on the Mississippi River . It was epic: nearly impassable wetlands, numbing cold, oppressive heat, barge traffic, Mark Twain, angry druggies, a police rescue, inspiring nature, solitude, torturous headwinds, engaging drunks, flying carp, a companionable gator and kindly angels.

The Mississippi trickles to life from Lake Itasca in north Minnesota and flows 2,500 miles to the Gulf. That’s as far as driving from Orlando to Los Angeles.

There are nearly 30 sets of locks and dams. They turn the upper half of the Mississippi into more of a lake than a river. There was no current tugging my boat to its destination.

The lower half combines forceful current and barges as big as buildings. To someone else, the vessels might appear sluggish. To me, they were swift monsters out to smush my boat.

All but a handful of days ended camping at the river, tucked into a pocket of woods, reigning as emperor of a tiny island or dwarfed by the vastness of moonscape sandbars.

Driftwood campfires were doable most nights. There were fiery sunsets, dazzling stars and tugboat searchlights blazing for navigation.

Paddling a canoe one mile, the internet says, needs a thousand strokes. That equates to 2.5 million from Itasca to the Gulf. Maybe 90 percent were a rhythmic chop-chop-chop with a kayak paddle, requiring no more attention than breathing.

That left space for podcasts, girlfriend calls and scribbling reflections such as this one:

The wind rippled and wrinkled the surface of the water.

A thin, wispy white horizon leading to a cloudless crescendo of blue sky.

The sun perched high and flooded the day with a warm embrace.

A thousand dancing diamonds blazed brilliantly across the opaque, muddy water.

It is something that cannot be bought or commodified, only earned.

Three days prior, I flew to Minneapolis with only the gear I could carry, took an Uber to a bus, bused four hours north to Bemidji, walked to U-Haul, drove a rented truck to buy a Facebook Marketplace canoe, then supplies at Walmart and slept in the truck’s cargo box.

Day 1: At Lake Itasca in northern Minnesota, I texted “starting trip” to family and friends.

Day 2: Tough going because of beaver dams and dense marsh. Saw an eagle and beaver close up. Slathered the boat with mud getting in and out to push it through water an inch deep.

Day 3: Damn beavers and their dams, dragging my canoe over them, one after another.

Day 5: Got emotional at the smell of a gas station’s hot food and thinking of a shower. Took a hotel room.

Day 6: After camping under a bear warning sign, I paddled six hours across Minnesota’s Lake Winnibigoshish, 104 square miles, the widest part of the Mississippi. It was calm.

Day 20: Never paddled into wind so strong. It would turn my boat, leaving no choice but to paddle backward to a bank to turn the boat back into the wind. Lost my temper.

From here, the river evolved into reservoirs, bordered by towns, parks and marinas, which provided a cultural setting for people to reside and recreate.

Day 23: Passed through St. Anthony Falls Lock in Minnesota: very weird steering a teensy vessel into a gargantuan structure.

Day 24: Texted home: “It’s like Florida. Laying bare on my sleeping pad drenched in sweat. It’s 98 degrees. Low on food. Canned tuna with hot sauce for dinner.”

Day 26: An a-hole powerboater, its passenger gazing at me blandly, roared by and flipped my canoe onto a rocky bank. A gashed toe bled a bit; no boat damage.

Day 27: Went into Six String Saloon in Maiden Rock, Wisconsin and ended up staying there until 2 a.m. A fight almost broke out from some guy flipping out. Wound up with friends. A man named Dave cooked me eggs and tater tots for breakfast. Mouth-watering after a month of cold oatmeal.

Day 29: Facebook post: “I’m not sure how I have the energy to slap the water with my paddle for 10 hours a day just to sleep on the ground without a shower.”

Day 32: Slept on a perfect beach near Guttenberg, Iowa, with a mass of driftwood for a big fire. Flames died as a super blue moon rose. Everything was vividly visible. It dropped to 48 degrees. I stayed warm, putting on all my clothes and using the tent’s rain fly as an extra blanket.

Day 43: Started a prescription of doxycycline because of a telltale rash of Lymes disease.

Day 46: Camped near an island above Fort Madison, Iowa, thick with white pelicans, too many to count. Huge wingspans, black-tipped wings, flying right over my head.

Day 49: At Hannibal, Missouri, locked the canoe to a tree. People veered from me. I reeked. Checked into a downtown hotel and dunked my clothes and self in a bath, making muddy water.

Day 50: Strolled through historic Hannibal for food and a beer, meeting all kinds of people, including in a dive bar eye-watering with cigarettes and accepting cash only. At closing, a woman invited everyone to her place. By 3 a.m., I was properly drunk as talk spun to raunchy hilariousness. Time to ease out.

Day 51: Spent hours in Hannibel’s museum honoring Mark Twain, surely a kindred spirit, with an eye on the horizon and a wit and wonder for what the hell is out there.

Day 54: Stopped at a marina north of St. Louis. They said I could camp on their property near the river. I ate at their restaurant and went to sleep around 11 p.m. At 1:30 a.m., a man, then a woman, who I took to be in charge of the marina, screamed at me that my phone had hacked into their iPad. They were drug-crazed, judging from the amped, confused yelling that I was acting on behalf of someone they were feuding with. He displayed a gun, took my phone, ransacked my stuff and wouldn’t let up. At daybreak, I jumped into the canoe, paddled to an island and used a satellite tracker device, which has simple messaging, to send a jumbled plea to my parents in Florida: “Im in a situation meth heads r holding phone hostage. Need cops threats.” They figured out which cops to call, who arrived in force. Asked to press charges, I declined. The couple was imprisoned by their own misery. I took a selfie with the guys who got me out of the jam.

Day 56: Last dam on the Mississippi. Finally, some amazing, helpful current.

Day 58: Hiked to a gas station in a small town, Chester, Illinois, spending $100 on supplies. Walking back to my canoe, I snacked on a turkey wrap. A sheriff’s car appeared and, yep, stopped. “Do I look weird?” I asked with a grin. “Yeah,” the driver answered with a poker face. “This is gonna sound weird,” I responded, before describing my travels. They actually got pretty interested.

From here, the river acquired serious intention: flowing powerfully, busy with barges and fewer people and more industry. It was lonelier. Historic drought had shriveled the river, leaving incredibly wide sandy shorelines that kept civilization at bay.

Day 61: The mighty Ohio River joins the Mississippi at Cairo, Illinois, for heavy congestion of barge traffic. Dove into the muddy river and dried by a bonfire. Glorious after 11 days without showering.

Day 67: Mud Island Marina! Friendly people at this Memphis stop gave me a ride to Walmart, a shower, a washing machine and a couch. The kind of people who make long solo trips seem not so lonely.

Day 70: Howling cold wind blasted sand into my tent. Hell of a night.

Day 71: Spooked a school of carp. One jumped over my boat. The next landed in the boat for a dramatic, thrashing and slimy encounter. Lugged it, slippery and heavy, to the water. Added “clean boat” to the chore list.

Day 74: At Greenville, Mississippi, John Keen of Mississippi River Angels, dedicated to paddlers, drove me to supplies, a shower and fried tamales, then a cheeseburger. He paddled the river in 2016. We spent four hours together. He’s a kind man with much patience.

Day 75: A barge powered up the river toward me. Its wake collided with a downriver current, spawning violent waves. I relied on years of whitewater guiding in North Carolina to thread a survival needle. I feared I couldn’t. Finally, I launched over the last wave to be left in silence, broken by my laughter. A friendly reminder that it ain’t over till it’s over.

Day 79: Bad day: unrelenting headwinds, broken canoe seat, malfunctioning solar charger. It was the first time I didn’t want to paddle, didn’t want to look at the boat, didn’t want to be on this river. I beat a favored paddle to smithereens against a beach, then remembered a Facebook friend had warned me not to quit on the worst day. The sun set, and stars twinkled. Tension eased. It’s hard to hate the river.

Day 80: I pulled up to a desolate sandbar that extended for miles. Poked around and walked up to a medium gator. Making camp didn’t bother it. I didn’t mind its company. It was still hanging out in the morning.

Day 86: Under heavy fog, north of Baton Rouge, I turned off the Mississippi into the Atchafalaya River, part of the Mississippi as a distributary or opposite of a tributary. Some geologists think this is where the full Mississippi would have gone if the government hadn’t forced the river through New Orleans. Paddling through Atchafalaya swamp — the largest wetland in the United States — in fog, listening to wildlife was fantastic.

Day 88: On the phone, river angel Danny Majors directed me to his cabin. He arrived later. We sat on the porch and swapped stories. I enjoyed his heavy Cajun accent, something I’ve never heard. He took me for Cajun cuisine, some cracklins and my first taste of boudin. Even half-starved, that was more calories than I knew what to do with. I slept on a bed in the cabin.

Day 89: Another carp encounter, one hitting the boat, one shooting under my left arm, across my lap and into the water. The swamp was divine, mosquitos ungodly.

Day 92: Getting closer to the Gulf with each turn in the river, paddling insanely hard against the incoming tide. Rounding a bend, a vast expanse of water appeared. I sat hushed, surprised and unprepared for the moment, then screamed: “That’s the [swearing] Gulf of Mexico!” Then, laughed, cried a bit and laughed. The final stretch to the last camp on a Gulf beach, Burns Point Park, about 20 miles southeast of Morgan City, Louisiana, was surreal. Having fought headwinds for so much of the trip, the wind had shifted generously and swept me across open water. It was the Mississippi’s sendoff nod of well done.

I had gotten skinny, callused my hands, wrecked my clothes with rips and stains and took on a weathered tan and wild hair. Traveling the Mississippi was a mental and physical test. I will never forget its people, timelessness and peaceful solitude amid open waters and giant sand bar s.

Lucas Spear, who graduated from Edgewater High and the University of South Florida, is pursuing a sales career.

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The 7 Best Mississippi River Cruises for 2024

T he more than 2,300-mile Mississippi River invites travelers to discover its multifaceted heritage, with a vast range of deeply rooted culture, music and history. A cruise is a fantastic way to discover many of the riverfront cities on a single trip, from the comfort of your modern riverboat or traditional paddle-wheeler.

The following Mississippi River cruise itineraries can help you choose from cruises of various lengths and options for the Lower and Upper Mississippi. Note that all fares are listed as double occupancy (based on two people per cabin), and that they might not reflect taxes, port fees or gratuities. The itinerary availability listed is also subject to change.

American Cruise Lines

American Cruise Lines operates small ships accommodating between 90 and 180 passengers that are built, flagged and crewed in the U.S. – and it's the only company in the world operating a 100% U.S.-flagged fleet of riverboats and cruise ships. ACL's itineraries traverse waterways across 35 states, with 11 itineraries dedicated to the Mississippi River. Cruisers can choose to sail on modern riverboats with a sleek interior design or while away their time aboard classic paddle-wheelers reminiscent of days gone by.

ACL offers variety as well as versatility: This line boasts both the longest and shortest sailings on this list with cruises ranging from eight to 60 days in length, including The Great United States. This inaugural 60-day voyage spans four major rivers and 20 states, making it the longest U.S. river cruise in history.

Complimentary hotel and transportation packages are available from every departure city before your cruise. You can book certain premium packages for added perks, such as two nights spent next door to Graceland in Memphis – with VIP tickets and a city tour included in the price.

Music Cities Cruise

Length: Eight days

Price: Starts at $3,610 per person

Spend a week getting lost in the sounds of the Memphis blues, rock 'n' roll and country music legends on the seven-night Music Cities Cruise. A hotel stay the night before your sailing is included, but embarking in Memphis means you also have the chance to splurge on a two-night pre-cruise package near Elvis' former home Graceland .

Ports of call include Paducah, Kentucky; Dover, Tennessee; and Clarksville, Tennessee, with an overnight in Nashville and an included excursion to a show at the Grand Ole Opry. Two scenic sailing days feature picturesque views of America's Heartland along the Mississippi, Ohio and Cumberland rivers as well as Lake Barkley.

2024 dates: In 2024, there are two available itineraries in September and November.

Grand Heartland Cruise: St. Paul to New Orleans

Length: 15 days

Price: Starts at $9,455 per person

This 15-day voyage allows you to explore America's rich history in towns along the Upper and Lower Mississippi River. The immersive voyage covers six states and 12 cities including St. Paul, Minnesota ; Dubuque, Iowa; St. Louis, Missouri ; Memphis, Tennessee; Natchez, Mississippi; Baton Rouge, Louisiana ; and more.

Take a step back in time while visiting Mark Twain's boyhood home in Hannibal, exploring stately historic estates in Natchez and Civil War sites in Vicksburg. At the end of a busy day ashore, you'll have plenty to chat about with fellow passengers during the evening cocktail hour.

2024 dates: American Heritage – ACL's traditional paddle-wheeler – and three modern riverboats set off on this journey from August to October in 2024.

Complete Mississippi River Cruise: New Orleans to St. Paul

Length: 22 days

Price: Starts at $14,935 per person

If you want to see the entire Mississippi in one shot, check out this multiweek sailing that begins in New Orleans and ends in St. Paul, Minnesota. Along the way, you'll sail 1,393 miles, visit 10 states and experience a staggering 20 ports of call as you tour Louisiana and then head northbound to Minnesota.

In the South, walk the battlefields of the Civil War and sample delicious Southern barbecue before listening to the rhythms of jazz, the blues and rock 'n' roll. Then, explore the small and larger cities along the upper parts of the river. Remember to take time to gaze out at the picturesque scenery and the rolling farmlands of America's Midwest before disembarking in St. Paul.

2024 dates: Three of ACL's modern riverboats sail this itinerary in May, June and August in 2024.

The Great United States

Length: 60 days

Price: Starts at $51,000

This two-month long journey – the longest domestic itinerary ever created – will check all the boxes for U.S. history and Civil War buffs, music and nature lovers, culinary enthusiasts, and beer and distilled spirits aficionados alike as the ship traverses America's iconic waterways through 20 states and 50 ports of call.

This epic journey showcases the natural beauty and living history of the U.S. from sea to shining sea. The sailing embarks in Portland, Oregon , on the Pacific Coast before traveling east to the Atlantic shore along four major rivers that highlight some of the country's most stunning coastlines. Upon arrival in New York Harbor, guests will have an unforgettable view of one of the most iconic landmarks in the U.S.: the Statue of Liberty .

Passengers can follow in the footsteps of Lewis and Clark along the Snake and Columbia rivers; cruise along Ol' Man River in search of Mark Twain and Elvis; see the vibrant colors of fall during peak season on the Hudson River; and take in the coastal breezes (and fresh seafood) along New England's rocky coastline.

This curated adventure also includes two flights: Jackson, Wyoming , to New Orleans as well as St. Paul to Portland, Maine , plus a land package through Glacier , Yellowstone and Grand Teton national parks. All-inclusive pricing covers the pre-cruise hotel stay, all flights and hotels between cruise segments, an ACL jacket and gear pack, daily excursions, all meals and beverages, gratuities and port charges, entertainment, and Wi-Fi.

2024 dates: The inaugural cruise sets sail on August 16, 2024.

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Viking River Cruises

Viking is no stranger to sailing Europe's rivers; the brand is synonymous with river cruising worldwide aboard its dozens of ships. However, Viking River Cruises is a newcomer to U.S. rivers, with its purpose-built ship: the 386-passenger Viking Mississippi. Looking to carve out its own niche in the American river cruising category, Viking claims it has the region's "first truly modern cruise ship" with its distinct Scandinavian design and expansive top sun deck with an infinity plunge pool.

Viking's mostly all-inclusive fares include a complimentary excursion in each port, destination lectures and performances, beer and wine at meals, free Wi-Fi, specialty coffees and teas, and more. The line offers five itineraries ranging in length from eight to 22 days along the Mighty Mississippi. Pre- and post-cruise extensions can be added to all voyages for an additional expense.

New Orleans & Southern Charms: Round-trip from New Orleans

Price: Starts at $3,999 per person

If you don't know which Viking Mississippi itinerary to choose, start here. A round-trip voyage from New Orleans is convenient for booking flights and offers an excellent opportunity to extend your stay in NOLA. Six guided tours are included across eight days, from the historic estates of Natchez to Vicksburg National Military Park. A stop in St. Francisville gives you the chance to marvel at some of the 140-plus buildings it has on the National Register of Historic Places.

If you extend your stay in New Orleans, plan to sample the local Creole cuisine and take in some of the city's nightly jazz entertainment. In the morning, grab a beignet and a steaming cup of chicory coffee au lait at the original Café du Monde in the French Market.

2024 dates: This itinerary is available on select dates in February, November and December.

Heart of the Delta: New Orleans to Memphis

Length: Nine days

Price: Starts at $4,299 per person

Similar to its round-trip New Orleans Southern Charms itinerary, the Heart of the Delta cruise begins in New Orleans and calls on the same five ports, before sailing through the Lower Mississippi and disembarking in Memphis. Enjoy scenic views of the serpentine river route – perhaps with expert commentary or a local cooking demonstration – and then take time to explore the birthplace of the Memphis blues, which is also a center of civil rights history.

2024 dates: In 2024, this cruise is available in February, March, April, May, June and November.

America's Great River: St. Paul to New Orleans

Price: Starts at $12,999 per person

This Viking voyage sails from St. Paul to New Orleans on a two-week trip that calls on 13 ports with one day of scenic sailing. This itinerary combines the best of Viking's other Mississippi sailings for an all-encompassing Midwestern and Southern experience with 12 guided tours.

Included in the fare is a tour of Graceland; a stroll through small-town Burlington, Iowa, to see Snake Alley, deemed the most crooked street in the world; and a visit to the National Eagle Center of Red Wing, among others. For an additional fee, hop on an airboat ride through the Atchafalaya Swamp in Baton Rouge or tour the Anheuser-Busch Brewery of St. Louis.

2024 dates: Viking has availability for this itinerary in July, September and October.

Want to cruise the Mississippi River? See the top cruises on GoToSea , a service of U.S. News.

FAQ Module : Travel - Top Mississippi River Cruises FAQs

Why Trust U.S. News Travel

Gwen Pratesi has been an avid cruiser since her early 20s. She has sailed on nearly every type of cruise ship built, including the newest megaships, paddle-wheelers on America's waterways, and an 18-stateroom river ship on the Mekong River in Vietnam and Cambodia. Most recently, she traveled on a small luxury expedition vessel in Antarctica and crossed the notorious Drake Passage twice. She covers the travel and culinary industries, specializing in cruises, for major publications including U.S. News & World Report.

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